藥物交互作用
Insulin glargine + Pentamidine
嚴重程度: 嚴重
Insulin glargine and Pentamidine: major interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Pentamidine can damage pancreatic beta cells, causing an initial hypoglycemia from insulin release, followed by hyperglycemia or diabetes. This makes insulin needs unpredictable.
用白話說明這項交互作用的意義
Insulin glargine and Pentamidine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Insulin glargine belongs to Endocrine; Pentamidine belongs to Anti Parasitic.
為什麼會發生
Pentamidine is toxic to pancreatic beta cells, causing early insulin release followed by insulin deficiency.
處置方式
Monitor blood glucose frequently during and after pentamidine therapy and adjust the insulin glargine dose promptly.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Insulin glargine 的其他交互作用
Pentamidine 的其他交互作用
常見問題
Can I take Insulin glargine with Pentamidine?
MediHelp rates the interaction as major. Insulin glargine and Pentamidine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Pentamidine can damage pancreatic beta cells, causing an initial hypoglycemia from insulin release, followed by hyperglycemia or diabetes. This makes insulin needs unpredictable.
How serious is the interaction between Insulin glargine and Pentamidine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose frequently during and after pentamidine therapy and adjust the insulin glargine dose promptly.
What other medicines interact with Insulin glargine?
MediHelp also lists interactions of Insulin glargine with, for example, Alogliptin-pioglitazone, Ethanol, Glimepiride-pioglitazone. The full list is on the Insulin glargine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。