跳至主要內容

藥物交互作用

Iron + Trientine

嚴重程度: 中度

Iron and Trientine: moderate interaction.

最後更新

僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Trientine chelates iron in the gut, lowering absorption of both trientine and iron. Iron deficiency can result, and trientine efficacy in Wilson disease may be reduced.

用白話說明這項交互作用的意義

Iron and Trientine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Iron belongs to Gastrointestinal Tract; Trientine belongs to Miscellaneous.

證據等級: Moderate

為什麼會發生

Chelation of iron by trientine in the gastrointestinal tract forms poorly absorbed complexes.

處置方式

Separate oral iron from trientine by at least 2 hours. Monitor iron indices and copper control during combined therapy.

可向藥師詢問的問題

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ 會員專屬

解鎖完整頁面

建立帳號並開始 Pro+ 試用,即可解鎖 Iron 與 Trientine 的完整臨床處置建議、補充說明、證據詳情及整張處方的交互作用檢查工具。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

在網頁版免費試用 Pro+ 14 天,無需信用卡。

常見問題

Can I take Iron with Trientine?

MediHelp rates the interaction as moderate. Iron and Trientine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Trientine chelates iron in the gut, lowering absorption of both trientine and iron. Iron deficiency can result, and trientine efficacy in Wilson disease may be reduced.

How serious is the interaction between Iron and Trientine?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate oral iron from trientine by at least 2 hours. Monitor iron indices and copper control during combined therapy.

What other medicines interact with Iron?

MediHelp also lists interactions of Iron with, for example, Acetohydroxamic acid, Aluminum hydroxide, Baloxavir marboxil. The full list is on the Iron page.

在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查

在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。

依 A–Z 瀏覽 · 藥物交互作用

取得 App 登入