藥品參考
Trientine
Trientine is a medicine in the class miscellaneous. It is used for wilson's disease.
- 藥物類別: Miscellaneous
- 用途: wilson's disease
最後更新 來源: US FDA label
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Miscellaneous
- 常見劑型
- 錠劑, 膠囊
- 常見規格
- 250 mg, 300 mg
- 已知交互作用
- 22 (中度: 9 · 輕微: 13)
- 商品名
- 4
- 國家與市場
- 2
用途
作用方式
Copper chelator that removes absorbed copper by forming a stable complex eliminated in urine; it also chelates copper in the intestinal tract, reducing copper absorption.
成人常用劑量（仿單摘要）
Stable Wilson's disease (de-coppered, penicillamine-tolerant): starting total daily dose 300 mg up to 3,000 mg orally in divided doses, two times daily; adjust by clinical assessment and copper monitoring; maximum 3,000 mg/day
懷孕與哺乳
- 懷孕
- Unknown Published data and decades of use have not identified drug-associated risks for birth defects or miscarriage, but animal studies showed embryo-fetal loss and fetal abnormalities. Monitor copper throughout pregnancy and use the minimum effective dose.
- 哺乳
- Unknown Data on detection in breastmilk are inconsistent; no adverse effects in breastfed infants reported. Weigh benefits of breastfeeding against maternal need.
已通報的副作用
- Abdominal pain
- Change of bowel habits
- Rash
- Alopecia
- Mood swings
禁忌症
- Hypersensitivity to trientine or any excipient in CUVRIOR.
哪些人需要特別留意
- Clinical symptoms, including neurological deterioration, may worsen at the start of therapy due to copper mobilization.
- Copper deficiency may develop; monitor closely, particularly in pregnancy.
- Iron deficiency may develop, especially in menstruating or pregnant women; iron may be given in short courses at least 2 hours apart from CUVRIOR.
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
重要交互作用 (22)
- Calcium + Trientine Moderate
- Carbonyl iron + Trientine Moderate
- Copper + Trientine Moderate
- Ferrous fumarate + Trientine Moderate
- Ferrous gluconate + Trientine Moderate
- Ferrous sulfate + Trientine Moderate
- Iron + Trientine Moderate
- Magnesium + Trientine Moderate
- Trientine + Zinc Moderate
- Acetazolamide + Trientine Minor
Pro+ 會員專屬
解鎖完整頁面
建立帳號並開始 Pro+ 試用，即可開啟 Trientine 的完整藥品專論：劑量、懷孕與哺乳、副作用、警示及所有交互作用。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Dosing in older adults
- How to give it
- Pharmacokinetics
- Patient counselling points
- Food interactions
在網頁版免費試用 Pro+ 14 天，無需信用卡。
常見問題
What is Trientine used for?
Trientine is a medicine in the class miscellaneous. It is used for Wilson's disease.
What side effects have been reported with Trientine?
Abdominal pain, Change of bowel habits, Rash, Alopecia, Mood swings.
Can Trientine be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Published data and decades of use have not identified drug-associated risks for birth defects or miscarriage, but animal studies showed embryo-fetal loss and fetal abnormalities. Monitor copper throughout pregnancy and use the minimum effective dose. Breastfeeding: Unknown. Data on detection in breastmilk are inconsistent; no adverse effects in breastfed infants reported. Weigh benefits of breastfeeding against maternal need.
What does Trientine interact with?
MediHelp lists 22 known interactions for Trientine. Moderate: 9 · Minor: 13. The most serious include Calcium, Carbonyl iron, Copper.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
