藥物交互作用
Measles mumps and rubella vaccine + Melphalan
嚴重程度: 禁忌併用
Measles mumps and rubella vaccine and Melphalan: contraindicated interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Melphalan causes marked myelosuppression and immunosuppression, so live attenuated vaccine viruses may replicate unchecked and cause disseminated infection. Vaccine efficacy is also reduced.
用白話說明這項交互作用的意義
Measles mumps and rubella vaccine and Melphalan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Measles mumps and rubella vaccine belongs to Miscellaneous; Melphalan belongs to Oncology.
為什麼會發生
Cytotoxic immunosuppression permits uncontrolled replication of live attenuated virus.
處置方式
Avoid live vaccines during melphalan therapy; give them only after immune recovery, usually at least 3 months after stopping.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Measles mumps and rubella vaccine 的其他交互作用
- Adalimumab + Measles mumps and rubella vaccine 禁忌併用
- Anakinra + Measles mumps and rubella vaccine 禁忌併用
- Antithymocyte globulin equine + Measles mumps and rubella vaccine 禁忌併用
- Antithymocyte globulin rabbit + Measles mumps and rubella vaccine 禁忌併用
- Azathioprine + Measles mumps and rubella vaccine 禁忌併用
- Basiliximab + Measles mumps and rubella vaccine 禁忌併用
Melphalan 的其他交互作用
常見問題
Can I take Measles mumps and rubella vaccine with Melphalan?
MediHelp rates the interaction as contraindicated. Measles mumps and rubella vaccine and Melphalan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Melphalan causes marked myelosuppression and immunosuppression, so live attenuated vaccine viruses may replicate unchecked and cause disseminated infection. Vaccine efficacy is also reduced.
How serious is the interaction between Measles mumps and rubella vaccine and Melphalan?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live vaccines during melphalan therapy; give them only after immune recovery, usually at least 3 months after stopping.
What other medicines interact with Measles mumps and rubella vaccine?
MediHelp also lists interactions of Measles mumps and rubella vaccine with, for example, Adalimumab, Anakinra, Antithymocyte globulin equine. The full list is on the Measles mumps and rubella vaccine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
