藥物交互作用
Measles mumps and rubella vaccine live + Tacrolimus
嚴重程度: 禁忌併用
Measles mumps and rubella vaccine live and Tacrolimus: contraindicated interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
The MMR vaccine contains live attenuated viruses. In tacrolimus-treated patients these viruses may replicate unchecked and cause vaccine-strain disease, and the immune response is likely to be poor.
用白話說明這項交互作用的意義
Measles mumps and rubella vaccine live and Tacrolimus are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
為什麼會發生
Calcineurin inhibition suppresses cellular immunity, permitting replication of live attenuated vaccine viruses.
處置方式
Do not give MMR vaccine to patients on tacrolimus. Vaccinate before transplant or immunosuppression where possible, and check immunity by serology.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Tacrolimus 的其他交互作用
常見問題
Can I take Measles mumps and rubella vaccine live with Tacrolimus?
MediHelp rates the interaction as contraindicated. Measles mumps and rubella vaccine live and Tacrolimus are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The MMR vaccine contains live attenuated viruses. In tacrolimus-treated patients these viruses may replicate unchecked and cause vaccine-strain disease, and the immune response is likely to be poor.
How serious is the interaction between Measles mumps and rubella vaccine live and Tacrolimus?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give MMR vaccine to patients on tacrolimus. Vaccinate before transplant or immunosuppression where possible, and check immunity by serology.
What other medicines interact with Tacrolimus?
MediHelp also lists interactions of Tacrolimus with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Cidofovir. The full list is on the Tacrolimus page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
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