藥物交互作用
Measles mumps rubella and varicella vaccine live + Methylprednisolone
嚴重程度: 禁忌併用
Measles mumps rubella and varicella vaccine live and Methylprednisolone: contraindicated interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
MMRV contains live attenuated viruses, including varicella, which can disseminate in patients receiving immunosuppressive methylprednisolone. The immune response may also be diminished.
用白話說明這項交互作用的意義
Measles mumps rubella and varicella vaccine live and Methylprednisolone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
為什麼會發生
Corticosteroid-induced suppression of cell-mediated immunity permits uncontrolled replication of live vaccine viruses.
處置方式
Do not administer during immunosuppressive steroid doses; postpone until steroids have been stopped for the recommended interval. Separate MMR and varicella vaccines are not safer, so use the same deferral.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Methylprednisolone 的其他交互作用
常見問題
Can I take Measles mumps rubella and varicella vaccine live with Methylprednisolone?
MediHelp rates the interaction as contraindicated. Measles mumps rubella and varicella vaccine live and Methylprednisolone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. MMRV contains live attenuated viruses, including varicella, which can disseminate in patients receiving immunosuppressive methylprednisolone. The immune response may also be diminished.
How serious is the interaction between Measles mumps rubella and varicella vaccine live and Methylprednisolone?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not administer during immunosuppressive steroid doses; postpone until steroids have been stopped for the recommended interval. Separate MMR and varicella vaccines are not safer, so use the same deferral.
What other medicines interact with Methylprednisolone?
MediHelp also lists interactions of Methylprednisolone with, for example, Bcg vaccine live, Measles mumps and rubella vaccine live, Measles vaccine. The full list is on the Methylprednisolone page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
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