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藥物交互作用

Olsalazine + Warfarin

嚴重程度: 輕微

Olsalazine and Warfarin: minor interaction.

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僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Olsalazine is a salicylate-derived aminosalicylate, and salicylates have been reported to potentiate warfarin in isolated cases. Systemic exposure to the active mesalamine is low, so the effect is likely modest.

用白話說明這項交互作用的意義

Olsalazine and Warfarin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Olsalazine belongs to Gastrointestinal Tract; Warfarin belongs to Cardiovascular.

證據等級: Low

為什麼會發生

Possible small additive effect of salicylate on coagulation; mechanism not firmly established.

處置方式

Check INR after starting or stopping olsalazine and adjust warfarin if the INR changes.

可向藥師詢問的問題

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ 會員專屬

解鎖完整頁面

建立帳號並開始 Pro+ 試用,即可解鎖 Olsalazine 與 Warfarin 的完整臨床處置建議、補充說明、證據詳情及整張處方的交互作用檢查工具。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

在網頁版免費試用 Pro+ 7 天,無需信用卡。

常見問題

Can I take Olsalazine with Warfarin?

MediHelp rates the interaction as minor. Olsalazine and Warfarin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Olsalazine is a salicylate-derived aminosalicylate, and salicylates have been reported to potentiate warfarin in isolated cases. Systemic exposure to the active mesalamine is low, so the effect is likely modest.

How serious is the interaction between Olsalazine and Warfarin?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check INR after starting or stopping olsalazine and adjust warfarin if the INR changes.

What other medicines interact with Warfarin?

MediHelp also lists interactions of Warfarin with, for example, Defibrotide, Ketorolac, Abciximab. The full list is on the Warfarin page.

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