藥品參考
Olsalazine
Olsalazine is a medicine in the class gastrointestinal tract. It is used for ulcerative colitis.
- 藥物類別: Gastrointestinal Tract
- 用途: ulcerative colitis
最後更新
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重點資訊
- 藥物類別
- Gastrointestinal Tract
- 常見劑型
- 膠囊
- 常見規格
- 250 mg
- 已知交互作用
- 1 (輕微: 1)
- 商品名
- 3
- 國家與市場
- 3
用途
作用方式
Converted to 5-aminosalicylic acid (mesalamine) by gastrointestinal flora which is thought to be the therapeutically active component; works topically rather than systemically.
成人常用劑量（仿單摘要）
Ulcerative Colitis Maintenance: 1g PO qDay in 2 divided doses, Take with food.
懷孕與哺乳
- 懷孕
- Safe It releases mesalamine (5-ASA); meta-analyses and cohort studies of mesalamine show no reliable link with birth defects or miscarriage. Rats had developmental effects at 5 to 20 times the human dose. Active ulcerative colitis itself raises pregnancy risks, so continue when needed.
- 哺乳
- Safe Little olsalazine passes into milk, but mesalamine metabolites do (mesalamine relative infant dose 0.1% or less). A few infants had diarrhoea. LactMed: not a reason to stop breastfeeding; watch the infant for diarrhoea. US label: weigh benefits.
已通報的副作用
- Headache
- Diarrhea
- Abdominal pain
- Nausea/vomiting
禁忌症
- Patients with known or suspected hypersensitivity to salicylates, aminosalicylates or their metabolites, or excipients
哪些人需要特別留意
- Patients with pre-existing skin conditions such as atopic dermatitis and atopic eczema have reported more severe photosensitivity reactions when receiving therapy.
- Cases of nephrolithiasis have been reported with use of mesalamine; active moiety in drug, including stones with 100% mesalamine content.
- advise patients to avoid sun exposure, wear protective clothing, and use a broad-spectrum sunscreen when outdoors
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
重要交互作用 (1)
- Olsalazine + Warfarin Minor
同類別的其他藥品
常見問題
What is Olsalazine used for?
Olsalazine is a medicine in the class gastrointestinal tract. It is used for Ulcerative colitis.
What side effects have been reported with Olsalazine?
Headache, Diarrhea, Abdominal pain, Nausea/vomiting.
Can Olsalazine be taken in pregnancy or while breastfeeding?
Pregnancy: Safe. It releases mesalamine (5-ASA); meta-analyses and cohort studies of mesalamine show no reliable link with birth defects or miscarriage. Rats had developmental effects at 5 to 20 times the human dose. Active ulcerative colitis itself raises pregnancy risks, so continue when needed. Breastfeeding: Safe. Little olsalazine passes into milk, but mesalamine metabolites do (mesalamine relative infant dose 0.1% or less). A few infants had diarrhoea. LactMed: not a reason to stop breastfeeding; watch the infant for diarrhoea. US label: weigh benefits.
What does Olsalazine interact with?
MediHelp lists 1 known interactions for Olsalazine. Minor: 1. The most serious include Warfarin.
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