Drug reference
baclofen
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Musculoskeletal (Muscle Relaxants)
Mechanism of action
Precise mechanism of action of baclofen is not fully understood, but Baclofen inhibits both monosynaptic and polysynaptic reflexes at the spinal level, possibly by decreasing excitatory neurotransmitter release from afferent terminals, although actions at supraspinal sites may also occur and contribute to its clinical effect.
Common side effects
- Dizziness
- Drowsiness
- Nausea
- Confusion
- Weakness
- Hypotonia
Related conditions
Frequently asked questions
What drug class is baclofen?
baclofen belongs to: Musculoskeletal.
How does baclofen work?
Precise mechanism of action of baclofen is not fully understood, but Baclofen inhibits both monosynaptic and polysynaptic reflexes at the spinal level, possibly by decreasing excitatory neurotransmitter release from afferent terminals, although actions at supraspinal sites may also occur and contribute to its clinical effect.
What are the common side effects of baclofen?
Dizziness, Drowsiness, Nausea, Confusion, Weakness, Hypotonia
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