Drug reference

ezogabine

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Drug class

Central Nervous System (Anti Epileptic Drugs)

Mechanism of action

Stabilizes neuronal KCNQ (Kv7) channels in the open position, increasing the stabilizing membrane current and preventing bursts of action potentials during the sustained depolarizations associated with seizures May also augment gamma-aminobutyric acid (GABA) mediated neurotransmission

Common side effects

  • Tremor
  • Dizziness
  • Somnolence
  • Fatigue
  • Nausea
  • Confusion
  • Vertigo

Related conditions

Frequently asked questions

What drug class is ezogabine?

ezogabine belongs to: Central Nervous System.

How does ezogabine work?

Stabilizes neuronal KCNQ (Kv7) channels in the open position, increasing the stabilizing membrane current and preventing bursts of action potentials during the sustained depolarizations associated with seizures May also augment gamma-aminobutyric acid (GABA) mediated neurotransmission

What are the common side effects of ezogabine?

Tremor, Dizziness, Somnolence, Fatigue, Nausea, Confusion, Vertigo

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

Browse A–Z · Drug reference