Drug reference
cefepime
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Anti Bacterial (Cephalosporins)
Mechanism of action
Fourth-generation cephalosporin; has gram-negative coverage comparable to ceftazidime but better gram-positive coverage (comparable to ceftriaxone); is zwitterion and rapidly penetrates gram-negative cells; is best beta-lactam for IM administration; has poor capacity to cross blood-brain barrier and thus is not used for treatment of meningitis
Common side effects
- Rash
- Positive Coombs test result without hemolysis
- Elevated alanine aminotransferase
- Hypophosphatemia
- Diarrhea
Contraindications
- Documented hypersensitivity to cefepime, penicillins, or other beta-lactam antibiotics
Related conditions
Frequently asked questions
What drug class is cefepime?
cefepime belongs to: Anti Bacterial.
How does cefepime work?
Fourth-generation cephalosporin; has gram-negative coverage comparable to ceftazidime but better gram-positive coverage (comparable to ceftriaxone); is zwitterion and rapidly penetrates gram-negative cells; is best beta-lactam for IM administration; has poor capacity to cross blood-brain barrier and thus is not used for treatment of meningitis
What are the common side effects of cefepime?
Rash, Positive Coombs test result without hemolysis, Elevated alanine aminotransferase, Hypophosphatemia, Diarrhea
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