Drug reference

chlorambucil

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Drug class

Oncology (Alkylating Agents)

Mechanism of action

Alkylating agent of nitrogen mustard family, crosslinks DNA and interferes with DNA replication and RNA transcription; cell cycle nonspecific

Common side effects

  • Neutropenia
  • Anemia
  • Leukopenia
  • Thrombocytopenia

Contraindications

  • Hypersensitivity or resistance; demonstrated resistance to chlorambucil previously

Related conditions

Frequently asked questions

What drug class is chlorambucil?

chlorambucil belongs to: Oncology.

How does chlorambucil work?

Alkylating agent of nitrogen mustard family, crosslinks DNA and interferes with DNA replication and RNA transcription; cell cycle nonspecific

What are the common side effects of chlorambucil?

Neutropenia, Anemia, Leukopenia, Thrombocytopenia

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