Drug reference
estradiol-norgestrel
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Endocrine (Gonadal Hormones)
Mechanism of action
Estradiol: Reduces LHRH release from hypothalamus, reduces gonadotropin release from pituitary; increase synthesis of DNA, RNA, and various proteins in target tissues. Norgestrel: Progestin; inhibits gonadotropin secretion from pituitary; prevents follicular maturation and ovulation, stimulates growth of mammary tissues
Common side effects
- Anorexia
- Edema
- Amenorrhea
- Weakness
- Breakthrough bleeding
- Change in menstrual flow
- Spotting
Related conditions
Frequently asked questions
What drug class is estradiol-norgestrel?
estradiol-norgestrel belongs to: Endocrine.
How does estradiol-norgestrel work?
Estradiol: Reduces LHRH release from hypothalamus, reduces gonadotropin release from pituitary; increase synthesis of DNA, RNA, and various proteins in target tissues. Norgestrel: Progestin; inhibits gonadotropin secretion from pituitary; prevents follicular maturation and ovulation, stimulates growth of mammary tissues
What are the common side effects of estradiol-norgestrel?
Anorexia, Edema, Amenorrhea, Weakness, Breakthrough bleeding, Change in menstrual flow, Spotting
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