Drug reference
isotretinoin
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Dermatology (Non-Antibiotic Topicals)
Mechanism of action
Retinoid; inhibits sebaceous gland function and keratinization; clinical improvement of nodular acne associated with sebum secretion reduction
Common side effects
- Pruritus
- Xerostomia
- Cheilitis
- Conjunctivitis
- Xerosis
- Epistaxis
- Dry nose
Known interactions (6)
- isotretinoin + minocycline Contraindicated
- isotretinoin + oxytetracycline Contraindicated
- doxycycline + isotretinoin Major
- isotretinoin + tetracycline Major
- isotretinoin + Piroxicam Moderate
- isotretinoin + Tizanidine Moderate
Related conditions
Frequently asked questions
What drug class is isotretinoin?
isotretinoin belongs to: Dermatology.
How does isotretinoin work?
Retinoid; inhibits sebaceous gland function and keratinization; clinical improvement of nodular acne associated with sebum secretion reduction
What are the common side effects of isotretinoin?
Pruritus, Xerostomia, Cheilitis, Conjunctivitis, Xerosis, Epistaxis, Dry nose
Which drugs interact with isotretinoin?
minocycline, oxytetracycline, doxycycline, tetracycline, Piroxicam, Tizanidine
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