Drug reference

L-methylfolate

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Drug class

Miscellaneous (Miscellaneous)

Mechanism of action

L-methylfolate is the primary biologically active isomer of folic acid and the primary form of folate in circulation, Folic acid is a precursor of tetrahydrofolic acid, which is involved as a cofactor for transformylation reactions. These reactions are involved in the biosynthesis of thymidylates and purines of nucleic acids The mechanism as an adjunct therapy in depression is unknown

Common side effects

  • Altered sleep patterns
  • Difficulty concentrating
  • Overactivity
  • Irritability

Frequently asked questions

What drug class is L-methylfolate?

L-methylfolate belongs to: Miscellaneous.

How does L-methylfolate work?

L-methylfolate is the primary biologically active isomer of folic acid and the primary form of folate in circulation, Folic acid is a precursor of tetrahydrofolic acid, which is involved as a cofactor for transformylation reactions. These reactions are involved in the biosynthesis of thymidylates and purines of nucleic acids The mechanism as an adjunct therapy in depression is unknown

What are the common side effects of L-methylfolate?

Altered sleep patterns, Difficulty concentrating, Overactivity, Irritability

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