Drug reference
norethisterone
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Endocrine (Progestin Preparations)
Mechanism of action
Norethisterone given at intermediate doses (5-10mg) suppresses ovulation via its effect on the pituitary. The endogenous production of oestrogens and progesterones are also suppressed, and the ectopic endometrium is converted to a decidua resembling that of pregnancy. In carcinoma norethisterone may act by pituitary inhibition or by direct action on tumor deposits.
Common side effects
- Anorexia
- Edema
- Amenorrhea
- Weakness
- Breakthrough bleeding
- Change in menstrual flowSpotting
- Deep vein thrombosis
Known interactions (1)
- acitretin + norethisterone Contraindicated
Related conditions
Frequently asked questions
What drug class is norethisterone?
norethisterone belongs to: Endocrine.
How does norethisterone work?
Norethisterone given at intermediate doses (5-10mg) suppresses ovulation via its effect on the pituitary. The endogenous production of oestrogens and progesterones are also suppressed, and the ectopic endometrium is converted to a decidua resembling that of pregnancy. In carcinoma norethisterone may act by pituitary inhibition or by direct action on tumor deposits.
What are the common side effects of norethisterone?
Anorexia, Edema, Amenorrhea, Weakness, Breakthrough bleeding, Change in menstrual flowSpotting, Deep vein thrombosis
Which drugs interact with norethisterone?
acitretin
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