Drug reference

medroxyprogesterone

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Drug class

Endocrine (Progestin Preparations)

Mechanism of action

Progestin inhibits the secretion of gonadotropins, which primarily prevents follicular maturation and ovulation and causes thickening cervical mucus; these actions contribute to its contraceptive effects. Suppression of serum estradiol concentrations is likely to be responsible for the therapeutic effect on endometriosis-associated pain

Common side effects

  • Injection site reactions
  • Abdominal Pain
  • Headache
  • Dysfunctional uterine bleeding
  • Amenorrhea
  • Vaginitis
  • Increased weight

Related conditions

Frequently asked questions

What drug class is medroxyprogesterone?

medroxyprogesterone belongs to: Endocrine.

How does medroxyprogesterone work?

Progestin inhibits the secretion of gonadotropins, which primarily prevents follicular maturation and ovulation and causes thickening cervical mucus; these actions contribute to its contraceptive effects. Suppression of serum estradiol concentrations is likely to be responsible for the therapeutic effect on endometriosis-associated pain

What are the common side effects of medroxyprogesterone?

Injection site reactions, Abdominal Pain, Headache, Dysfunctional uterine bleeding, Amenorrhea, Vaginitis, Increased weight

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