Drug reference

propylthiouracil

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Drug class

Endocrine (Thyroid Drugs)

Mechanism of action

Inhibits synthesis of thyroid hormone by blocking oxidation of iodine in thyroid gland; blocks synthesis of T4 and T3

Common side effects

  • Drowsiness
  • Fever
  • Agranulocytosis
  • Dermatologic reactions
  • Hepatitis
  • Aplastic anemia
  • Polyarthritis

Related conditions

Frequently asked questions

What drug class is propylthiouracil?

propylthiouracil belongs to: Endocrine.

How does propylthiouracil work?

Inhibits synthesis of thyroid hormone by blocking oxidation of iodine in thyroid gland; blocks synthesis of T4 and T3

What are the common side effects of propylthiouracil?

Drowsiness, Fever, Agranulocytosis, Dermatologic reactions, Hepatitis, Aplastic anemia, Polyarthritis

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