Drug reference
metoprolol
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Cardiovascular (Beta Blockers)
Mechanism of action
Blocks response to beta-adrenergic stimulation; cardioselective for beta1 receptors at low doses, with little or no effect on beta2 receptors
Common side effects
- Pruritus
- Dizziness
- Headache
- Depression
- Tiredness
- Diarrhea
Contraindications
- Hypertension and angina: Sinus bradycardia, 2°/3° heart block, cardiogenic shock, sick sinus syndrome (unless permanent pacemaker in place), severe peripheral vascular disease, pheochromocytoma
- Myocardial infarction: Severe sinus bradycardia, heart rate <45 beats/min, systolic BP <100 mmHg, significant first-degree heart block ((PR interval at least 0.24 seconds), 2°/3° heart block, moderate-to-severe cardiac failure
- Second- and third-degree heart block, deompensated heart failure, sick sinus syndrome (except in patients with functioning artificial pacemaker), severe bradycardia, cardiogenic shock
- Severe bradycardia, second or third degree heart block, cardiogenic shock, decompensated heart failure, sick sinus syndrome (unless a permanent pacemaker is in place), and in patients who are hypersensitive to any component of this product
Known interactions (5)
- metoprolol + verapamil Major
- aspirin + metoprolol Moderate
- chlorpromazine + metoprolol Moderate
- Digoxin + metoprolol Moderate
- isosorbide mononitrate + metoprolol Moderate
Related conditions
Frequently asked questions
What drug class is metoprolol?
metoprolol belongs to: Cardiovascular.
How does metoprolol work?
Blocks response to beta-adrenergic stimulation; cardioselective for beta1 receptors at low doses, with little or no effect on beta2 receptors
What are the common side effects of metoprolol?
Pruritus, Dizziness, Headache, Depression, Tiredness, Diarrhea
Which drugs interact with metoprolol?
verapamil, aspirin, chlorpromazine, Digoxin, isosorbide mononitrate
Full monographs, dosing and an interaction checker in the MediHelp app
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