Drug reference
nalbuphine
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Musculoskeletal (Opioids)
Mechanism of action
Narcotic agonist-analgesic of kappa opiate receptors and partial antagonist of mu opiate receptors; inhibits ascending pain pathways, thus altering response to pain; produces analgesia, respiratory depression, and sedation
Common side effects
- Sedation
- Dizziness
- Headache
- Xerostomia
- Clamminess
Contraindications
- Significant respiratory depression Diarrhea associated with toxins, gastrointestinal obstruction, including pseudomembranous colitis Acute or severe bronchial asthma, bradycardia, inflammatory bowel disease
Related conditions
Frequently asked questions
What drug class is nalbuphine?
nalbuphine belongs to: Musculoskeletal.
How does nalbuphine work?
Narcotic agonist-analgesic of kappa opiate receptors and partial antagonist of mu opiate receptors; inhibits ascending pain pathways, thus altering response to pain; produces analgesia, respiratory depression, and sedation
What are the common side effects of nalbuphine?
Sedation, Dizziness, Headache, Xerostomia, Clamminess
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