Drug reference

orphenadrin

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Drug class

Musculoskeletal (Muscle Relaxants)

Mechanism of action

May work through central atropine-like effect; anticholinergic activity in brain stem; has euphorigenic and analgesic properties

Common side effects

  • Dry mouth
  • Lightheadedness
  • Drowsiness
  • Urinary retention
  • Weakness
  • Blurred vision, mydriasis
  • Tachycardia

Contraindications

  • Hypersensitivity Narrow-angle glaucoma Pyloric/duodenal obstruction, BPH, stenosing peptic ulcers, cardiospasm (mega-esophagus), myasthenia gravis, obstructive uropathy, paralytic ileus, ulcerative colitis, toxic megacolon, achalasia

Related conditions

Frequently asked questions

What drug class is orphenadrin?

orphenadrin belongs to: Musculoskeletal.

How does orphenadrin work?

May work through central atropine-like effect; anticholinergic activity in brain stem; has euphorigenic and analgesic properties

What are the common side effects of orphenadrin?

Dry mouth, Lightheadedness, Drowsiness, Urinary retention, Weakness, Blurred vision, mydriasis, Tachycardia

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