Drug reference
palonosetron
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Gastrointestinal Tract (5-HT3 Antagonist)
Mechanism of action
Selective 5-HT3 receptor antagonist; palonosetron binds to 5-HT3 receptors both in peripheral and central nervous system with primary effects in GI tract.
Common side effects
- Prolonged QT interval
- Constipation
- Dizziness
- Anxiety
Contraindications
- Hypersensitivity to drug, other selective 5-HT3 receptor antagonists (eg, granisetron), or excipients
Related conditions
Frequently asked questions
What drug class is palonosetron?
palonosetron belongs to: Gastrointestinal Tract.
How does palonosetron work?
Selective 5-HT3 receptor antagonist; palonosetron binds to 5-HT3 receptors both in peripheral and central nervous system with primary effects in GI tract.
What are the common side effects of palonosetron?
Prolonged QT interval, Constipation, Dizziness, Anxiety
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