Drug reference
papaverine
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Cardiovascular (Vasodilators)
Mechanism of action
Smooth muscle spasmolytic via inhibition of oxidative phosphorylation & interference with Ca++ during muscle contraction as well as increase in cAMP from inhibition of cyclic nucleotide phosphodiesterase; most pronounced effect on blood vessels, including coronary, cerebral, pulmonary, gastrointestinal sphincter relaxation & peripheral arteries
Common side effects
- BP changes
- Depression
- Abdominal distress
- Tachycardia
Related conditions
Frequently asked questions
What drug class is papaverine?
papaverine belongs to: Cardiovascular.
How does papaverine work?
Smooth muscle spasmolytic via inhibition of oxidative phosphorylation & interference with Ca++ during muscle contraction as well as increase in cAMP from inhibition of cyclic nucleotide phosphodiesterase; most pronounced effect on blood vessels, including coronary, cerebral, pulmonary, gastrointestinal sphincter relaxation & peripheral arteries
What are the common side effects of papaverine?
BP changes, Depression, Abdominal distress, Tachycardia
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