Drug reference
phenobarbitone
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Central Nervous System (Barbiturates)
Mechanism of action
Depresses sensory and motor cortex, cerebellum Antiseizure activity occurs primarily where GABA mediates neurotransmission Hypnotic effects of barbiturates result from activity at GABA receptor in the polysynaptic midbrain reticular formation (controls CNS arousal)
Common side effects
- Dizziness
- Drowsiness
- Headache
- Fatigue
- Respiratory depression
- Ataxia
- Dysarthria
Related conditions
Frequently asked questions
What drug class is phenobarbitone?
phenobarbitone belongs to: Central Nervous System.
How does phenobarbitone work?
Depresses sensory and motor cortex, cerebellum Antiseizure activity occurs primarily where GABA mediates neurotransmission Hypnotic effects of barbiturates result from activity at GABA receptor in the polysynaptic midbrain reticular formation (controls CNS arousal)
What are the common side effects of phenobarbitone?
Dizziness, Drowsiness, Headache, Fatigue, Respiratory depression, Ataxia, Dysarthria
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