Drug reference
atovaquone-proguanil
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Anti Parasitic (Anti Malaria)
Mechanism of action
Antiparasitic activity. Atovaquone: Selective inhibitor of parasite mitochondrial electron transport. Proguanil: Primary effect through metabolite cycloguanil, a dihydrofolate reductase inhibitor in malaria parasite, which leads to disruption of deoxythymidylate synthesis
Common side effects
- Asthenia
- Vomiting
- Headache
- Nausea
- Transaminases increased
- Abdominal pain
Related conditions
Frequently asked questions
What drug class is atovaquone-proguanil?
atovaquone-proguanil belongs to: Anti Parasitic.
How does atovaquone-proguanil work?
Antiparasitic activity. Atovaquone: Selective inhibitor of parasite mitochondrial electron transport. Proguanil: Primary effect through metabolite cycloguanil, a dihydrofolate reductase inhibitor in malaria parasite, which leads to disruption of deoxythymidylate synthesis
What are the common side effects of atovaquone-proguanil?
Asthenia, Vomiting, Headache, Nausea, Transaminases increased, Abdominal pain
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