Drug reference
tamoxifen
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Endocrine (SERMs)
Mechanism of action
Selective estrogen receptor modulator: nonsteroid with potent antiestrogenic effects in breast (but may be estrogen agonist in uterus); has cytostatic effect rather than cytocidal effects (cells accumulate in Go and G1 phase of the cell cycle)
Common side effects
- Bone pain
- Hot flashes
- Oligomenorrhea
- Amenorrhea
- Vaginal discharge
- Menstrual changes
- Cataracts
Known interactions (2)
- anastrozole + tamoxifen Major
- paroxetine + tamoxifen Major
Related conditions
Frequently asked questions
What drug class is tamoxifen?
tamoxifen belongs to: Endocrine.
How does tamoxifen work?
Selective estrogen receptor modulator: nonsteroid with potent antiestrogenic effects in breast (but may be estrogen agonist in uterus); has cytostatic effect rather than cytocidal effects (cells accumulate in Go and G1 phase of the cell cycle)
What are the common side effects of tamoxifen?
Bone pain, Hot flashes, Oligomenorrhea, Amenorrhea, Vaginal discharge, Menstrual changes, Cataracts
Which drugs interact with tamoxifen?
anastrozole, paroxetine
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