Drug reference
vedolizumab
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Gastrointestinal Tract (Monoclonal antibody(GIT))
Mechanism of action
Recombinant humanized monoclonal antibody that binds specifically to α4β7 integrin and blocks the interaction of α4β7 integrin with mucosal addressin cell adhesion molecule-1 (MAdCAM-1) and inhibits the migration of memory T-lymphocytes across the endothelium into inflamed gastrointestinal parenchymal tissue.
Common side effects
- Nasopharyngitis
- Arthralgia
- Headache
- Nausea
- Pyrexia
Contraindications
- Hypersensitivity
Related conditions
Frequently asked questions
What drug class is vedolizumab?
vedolizumab belongs to: Gastrointestinal Tract.
How does vedolizumab work?
Recombinant humanized monoclonal antibody that binds specifically to α4β7 integrin and blocks the interaction of α4β7 integrin with mucosal addressin cell adhesion molecule-1 (MAdCAM-1) and inhibits the migration of memory T-lymphocytes across the endothelium into inflamed gastrointestinal parenchymal tissue.
What are the common side effects of vedolizumab?
Nasopharyngitis, Arthralgia, Headache, Nausea, Pyrexia
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