Drug reference
natalizumab
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Gastrointestinal Tract (Monoclonal antibody(GIT))
Mechanism of action
Recombinant humanized monoclonal antibody that binds to the α4-subunit of α4β1 and α4β7 integrins, prevents leukocyte-endothelial adhesion and leukocyte extravasation.
Common side effects
- Fatigue
- Sinusitis
- Urinary urgency/frequency
- Vaginal infections
- Diarrhea
Contraindications
- Hypersensitivity Active/history of progressive multifocal leukoencephalopathy
Related conditions
Frequently asked questions
What drug class is natalizumab?
natalizumab belongs to: Gastrointestinal Tract.
How does natalizumab work?
Recombinant humanized monoclonal antibody that binds to the α4-subunit of α4β1 and α4β7 integrins, prevents leukocyte-endothelial adhesion and leukocyte extravasation.
What are the common side effects of natalizumab?
Fatigue, Sinusitis, Urinary urgency/frequency, Vaginal infections, Diarrhea
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