Drug interactions
Abemaciclib + Clarithromycin
Severity: Major
Abemaciclib and Clarithromycin: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Clarithromycin raises exposure to abemaciclib and its active metabolites, increasing the risk of diarrhea, neutropenia and hepatotoxicity.
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Other interactions of Clarithromycin
Other interactions of Abemaciclib
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