Drug interactions
Aluminum hydroxide + Amlodipine-benazepril
Severity: Minor
Aluminum hydroxide and Amlodipine-benazepril: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Antacids containing aluminum may reduce the absorption of ACE inhibitors such as benazepril, potentially lessening the blood pressure effect. The effect is modest and variable.
What this interaction means in plain words
Aluminum hydroxide and Amlodipine-benazepril have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Aluminum hydroxide belongs to Gastrointestinal Tract; Amlodipine-benazepril belongs to Cardiovascular.
Why it happens
Antacid binding or raised gastric pH may reduce ACE inhibitor absorption.
What to do
Separate benazepril and the antacid by at least two hours. Monitor blood pressure if antacids are used regularly.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine-benazepril
- Aliskiren + Amlodipine-benazepril Contraindicated
- Aldesleukin + Amlodipine-benazepril Major
- Amifostine + Amlodipine-benazepril Major
- Amiloride + Amlodipine-benazepril Major
Other interactions of Aluminum hydroxide
Frequently asked questions
Can I take Aluminum hydroxide with Amlodipine-benazepril?
MediHelp rates the interaction as minor. Aluminum hydroxide and Amlodipine-benazepril have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Antacids containing aluminum may reduce the absorption of ACE inhibitors such as benazepril, potentially lessening the blood pressure effect. The effect is modest and variable.
How serious is the interaction between Aluminum hydroxide and Amlodipine-benazepril?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate benazepril and the antacid by at least two hours. Monitor blood pressure if antacids are used regularly.
What other medicines interact with Amlodipine-benazepril?
MediHelp also lists interactions of Amlodipine-benazepril with, for example, Aliskiren, Aldesleukin, Amifostine. The full list is on the Amlodipine-benazepril page.
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