Drug interactions
Aluminum hydroxide + Celecoxib
Severity: Minor
Aluminum hydroxide and Celecoxib: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Co-administration of an aluminum-containing antacid with celecoxib modestly lowers celecoxib exposure. The reduction is generally small and unlikely to cause loss of analgesic effect for most patients.
What this interaction means in plain words
Aluminum hydroxide and Celecoxib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Aluminum hydroxide belongs to Gastrointestinal Tract; Celecoxib belongs to Musculoskeletal.
Why it happens
The antacid may slightly reduce celecoxib absorption in the gut, though the mechanism is not firmly established.
What to do
No routine adjustment is needed; if desired, separate doses by about 2 hours. Reassess pain control if response seems reduced.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Aluminum hydroxide
Other interactions of Celecoxib
- Aceclofenac + Celecoxib Major
- Acemetacin + Celecoxib Major
- Amiloride + Celecoxib Major
Frequently asked questions
Can I take Aluminum hydroxide with Celecoxib?
MediHelp rates the interaction as minor. Aluminum hydroxide and Celecoxib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Co-administration of an aluminum-containing antacid with celecoxib modestly lowers celecoxib exposure. The reduction is generally small and unlikely to cause loss of analgesic effect for most patients.
How serious is the interaction between Aluminum hydroxide and Celecoxib?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed; if desired, separate doses by about 2 hours. Reassess pain control if response seems reduced.
What other medicines interact with Aluminum hydroxide?
MediHelp also lists interactions of Aluminum hydroxide with, for example, Ciprofloxacin, Deferasirox, Dolutegravir. The full list is on the Aluminum hydroxide page.
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