Drug interactions
Aluminum hydroxide + Digoxin
Severity: Minor
Aluminum hydroxide and Digoxin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Antacids may reduce digoxin absorption when taken together, which can lower serum levels. The effect is typically small and avoided by dose separation.
What this interaction means in plain words
Aluminum hydroxide and Digoxin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Aluminum hydroxide belongs to Gastrointestinal Tract; Digoxin belongs to Cardiovascular.
Why it happens
Adsorption or binding of digoxin in the gut by aluminum antacids, reducing absorption.
What to do
Separate digoxin and the antacid by at least 2 hours and monitor digoxin levels if control changes.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Aluminum hydroxide
Other interactions of Digoxin
- Adagrasib + Digoxin Major
Frequently asked questions
Can I take Aluminum hydroxide with Digoxin?
MediHelp rates the interaction as minor. Aluminum hydroxide and Digoxin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Antacids may reduce digoxin absorption when taken together, which can lower serum levels. The effect is typically small and avoided by dose separation.
How serious is the interaction between Aluminum hydroxide and Digoxin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate digoxin and the antacid by at least 2 hours and monitor digoxin levels if control changes.
What other medicines interact with Aluminum hydroxide?
MediHelp also lists interactions of Aluminum hydroxide with, for example, Ciprofloxacin, Deferasirox, Dolutegravir. The full list is on the Aluminum hydroxide page.
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