Drug interactions
Amiodarone + Anastrozole
Severity: Minor
Amiodarone and Anastrozole: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
No meaningful interaction is established; anastrozole is a weak in vitro CYP3A4 inhibitor and does not significantly change drug levels clinically. Any rise in amiodarone is theoretical.
What this interaction means in plain words
Amiodarone and Anastrozole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amiodarone belongs to Cardiovascular; Anastrozole belongs to Oncology.
Why it happens
Theoretical weak CYP3A4 inhibition by anastrozole; no established clinical mechanism.
What to do
No action beyond routine amiodarone ECG monitoring is needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amiodarone
- Amiodarone + Amisulpride Contraindicated
- Amiodarone + Arsenic trioxide Contraindicated
- Amiodarone + Dofetilide Contraindicated
- Amiodarone + Dronedarone Contraindicated
- Amiodarone + Droperidol Contraindicated
- Amiodarone + Eliglustat Contraindicated
Other interactions of Anastrozole
- Anastrozole + Bazedoxifene / conjugated estrogens Contraindicated
- Anastrozole + Bazedoxifene-conjugated estrogens Contraindicated
- Anastrozole + Conjugated estrogens Contraindicated
- Anastrozole + Estradiol Contraindicated
- Anastrozole + Estrogens conjugated synthetic Contraindicated
- Anastrozole + Estrogens esterified Contraindicated
Frequently asked questions
Can I take Amiodarone with Anastrozole?
MediHelp rates the interaction as minor. Amiodarone and Anastrozole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. No meaningful interaction is established; anastrozole is a weak in vitro CYP3A4 inhibitor and does not significantly change drug levels clinically. Any rise in amiodarone is theoretical.
How serious is the interaction between Amiodarone and Anastrozole?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action beyond routine amiodarone ECG monitoring is needed.
What other medicines interact with Amiodarone?
MediHelp also lists interactions of Amiodarone with, for example, Amisulpride, Arsenic trioxide, Dofetilide. The full list is on the Amiodarone page.
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