Drug interactions
Amiodarone + Empagliflozin-metformin
Severity: Minor
Amiodarone and Empagliflozin-metformin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Amiodarone may inhibit renal and hepatic transport of metformin and could raise its exposure. Any effect is probably modest, and clinical evidence is limited.
What this interaction means in plain words
Amiodarone and Empagliflozin-metformin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amiodarone belongs to Cardiovascular; Empagliflozin-metformin belongs to Endocrine.
Why it happens
Possible inhibition of organic cation transporters involved in metformin clearance.
What to do
No routine adjustment is needed. Monitor glycemic control and renal function, and watch for gastrointestinal intolerance.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Empagliflozin-metformin
Other interactions of Amiodarone
- Amiodarone + Amisulpride Contraindicated
- Amiodarone + Arsenic trioxide Contraindicated
- Amiodarone + Dofetilide Contraindicated
- Amiodarone + Dronedarone Contraindicated
- Amiodarone + Droperidol Contraindicated
- Amiodarone + Eliglustat Contraindicated
Frequently asked questions
Can I take Amiodarone with Empagliflozin-metformin?
MediHelp rates the interaction as minor. Amiodarone and Empagliflozin-metformin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Amiodarone may inhibit renal and hepatic transport of metformin and could raise its exposure. Any effect is probably modest, and clinical evidence is limited.
How serious is the interaction between Amiodarone and Empagliflozin-metformin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed. Monitor glycemic control and renal function, and watch for gastrointestinal intolerance.
What other medicines interact with Empagliflozin-metformin?
MediHelp also lists interactions of Empagliflozin-metformin with, for example, Contrast media, Diatrizoate meglumine / diatrizoate, Diatrizoate. The full list is on the Empagliflozin-metformin page.
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