Drug interactions
Amlodipine + Etrasimod
Severity: Minor
Amlodipine and Etrasimod: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Etrasimod can transiently slow heart rate and AV conduction at initiation. Amlodipine is a dihydropyridine without significant direct nodal effects, so the interaction is limited. Additive blood pressure lowering is possible.
What this interaction means in plain words
Amlodipine and Etrasimod have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amlodipine belongs to Cardiovascular; Etrasimod belongs to Gastrointestinal Tract.
Why it happens
Possible additive hemodynamic effects; amlodipine has little direct effect on cardiac conduction.
What to do
Follow standard etrasimod first-dose cardiac precautions and monitor heart rate and blood pressure after initiation.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Amlodipine and Etrasimod, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Amlodipine
- Amifostine + Amlodipine Major
- Amlodipine + Ombitasvir / paritaprevir / ritonavir and dasabuvir Major
- Activated Charcoal + Amlodipine Moderate
- Aldesleukin + Amlodipine Moderate
- Alfuzosin + Amlodipine Moderate
- Amlodipine + Apalutamide Moderate
Other interactions of Etrasimod
- Abatacept + Etrasimod Major
- Amiodarone + Etrasimod Major
- Anagrelide + Etrasimod Major
- Anakinra + Etrasimod Major
- Anti-thymocyte + Etrasimod Major
- Asenapine + Etrasimod Major
Frequently asked questions
Can I take Amlodipine with Etrasimod?
MediHelp rates the interaction as minor. Amlodipine and Etrasimod have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Etrasimod can transiently slow heart rate and AV conduction at initiation. Amlodipine is a dihydropyridine without significant direct nodal effects, so the interaction is limited. Additive blood pressure lowering is possible.
How serious is the interaction between Amlodipine and Etrasimod?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Follow standard etrasimod first-dose cardiac precautions and monitor heart rate and blood pressure after initiation.
What other medicines interact with Amlodipine?
MediHelp also lists interactions of Amlodipine with, for example, Amifostine, Ombitasvir / paritaprevir / ritonavir and dasabuvir, Activated Charcoal. The full list is on the Amlodipine page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
