Drug interactions
Amlodipine + Timolol
Severity: Minor
Amlodipine and Timolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Amlodipine is a dihydropyridine calcium channel blocker, and combining it with a beta-blocker is common in hypertension and angina. Blood pressure lowering is additive and occasional hypotension may occur, and systemically absorbed timolol may add mild heart rate slowing.
What this interaction means in plain words
Amlodipine and Timolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amlodipine belongs to Cardiovascular; Timolol belongs to Cardiovascular.
Why it happens
Complementary antihypertensive effects from vasodilation and beta-blockade.
What to do
Monitor blood pressure and heart rate after starting or adjusting either drug. No routine dose change is needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Timolol
- Acebutolol + Timolol Major
- Aldesleukin + Timolol Major
- Amifostine + Timolol Major
- Amiodarone + Timolol Major
- Arformoterol + Timolol Major
- Atenolol-chlorthalidone + Timolol Major
Other interactions of Amlodipine
- Amifostine + Amlodipine Major
- Amlodipine + Ombitasvir / paritaprevir / ritonavir and dasabuvir Major
- Activated Charcoal + Amlodipine Moderate
- Aldesleukin + Amlodipine Moderate
- Alfuzosin + Amlodipine Moderate
- Amlodipine + Apalutamide Moderate
Frequently asked questions
Can I take Amlodipine with Timolol?
MediHelp rates the interaction as minor. Amlodipine and Timolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Amlodipine is a dihydropyridine calcium channel blocker, and combining it with a beta-blocker is common in hypertension and angina. Blood pressure lowering is additive and occasional hypotension may occur, and systemically absorbed timolol may add mild heart rate slowing.
How serious is the interaction between Amlodipine and Timolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate after starting or adjusting either drug. No routine dose change is needed.
What other medicines interact with Timolol?
MediHelp also lists interactions of Timolol with, for example, Acebutolol, Aldesleukin, Amifostine. The full list is on the Timolol page.
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