Drug interactions
Amlodipine-benazepril + Cariprazine
Severity: Moderate
Amlodipine-benazepril and Cariprazine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cariprazine can cause orthostatic hypotension and may enhance the effect of amlodipine and benazepril. Dizziness, syncope and falls are the main risks.
What this interaction means in plain words
Amlodipine-benazepril and Cariprazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amlodipine-benazepril belongs to Cardiovascular; Cariprazine belongs to Central Nervous System.
Why it happens
Additive hypotensive pharmacodynamic effects.
What to do
Monitor blood pressure and orthostatic symptoms during initiation and dose changes. Adjust antihypertensive doses if symptomatic.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Amlodipine-benazepril
- Aliskiren + Amlodipine-benazepril Contraindicated
- Amlodipine-benazepril + Sacubitril / valsartan Contraindicated
- Aldesleukin + Amlodipine-benazepril Major
- Amifostine + Amlodipine-benazepril Major
- Amiloride + Amlodipine-benazepril Major
- Amlodipine-benazepril + Azilsartan Major
Other interactions of Cariprazine
Frequently asked questions
Can I take Amlodipine-benazepril with Cariprazine?
MediHelp rates the interaction as moderate. Amlodipine-benazepril and Cariprazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cariprazine can cause orthostatic hypotension and may enhance the effect of amlodipine and benazepril. Dizziness, syncope and falls are the main risks.
How serious is the interaction between Amlodipine-benazepril and Cariprazine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and orthostatic symptoms during initiation and dose changes. Adjust antihypertensive doses if symptomatic.
What other medicines interact with Amlodipine-benazepril?
MediHelp also lists interactions of Amlodipine-benazepril with, for example, Aliskiren, Sacubitril / valsartan, Aldesleukin. The full list is on the Amlodipine-benazepril page.
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