Drug reference
cariprazine
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Central Nervous System (Anti Psychotic (atypical))
Mechanism of action
Efficacy could be mediated through a combination of partial agonist activity at central dopamine (D2) and serotonin 5-HT1A receptors Forms 2 major metabolites, desmethyl cariprazine (DCAR) and didesmethyl cariprazine (DDCAR), that have in vitro receptor binding profiles similar to the parent drug
Common side effects
- Extrapyramidal symptoms
- Insomnia
- Constipation
- Headache
- Akathisia
- Parkinsonism
Known interactions (12)
- amisulpride + cariprazine Major
- carbamazepine + cariprazine Major
- cariprazine + enzalutamide Major
- cariprazine + phenytoin Major
- bosentan + cariprazine Moderate
- cariprazine + dexamethasone Moderate
- cariprazine + dexamethasone-tobramycin Moderate
- cariprazine + efavirenz Moderate
- cariprazine + eslicarbazepine Moderate
- cariprazine + nevirapine Moderate
- cariprazine + oxcarbazepine Moderate
- cariprazine + rifabutin Moderate
Related conditions
Frequently asked questions
What drug class is cariprazine?
cariprazine belongs to: Central Nervous System.
How does cariprazine work?
Efficacy could be mediated through a combination of partial agonist activity at central dopamine (D2) and serotonin 5-HT1A receptors Forms 2 major metabolites, desmethyl cariprazine (DCAR) and didesmethyl cariprazine (DDCAR), that have in vitro receptor binding profiles similar to the parent drug
What are the common side effects of cariprazine?
Extrapyramidal symptoms, Insomnia, Constipation, Headache, Akathisia, Parkinsonism
Which drugs interact with cariprazine?
amisulpride, carbamazepine, enzalutamide, phenytoin, bosentan, dexamethasone, dexamethasone-tobramycin, efavirenz, eslicarbazepine, nevirapine, oxcarbazepine, rifabutin
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