Drug interactions
Amlodipine-benazepril + Cisatracurium
Severity: Moderate
Amlodipine-benazepril and Cisatracurium: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Calcium channel blockers may potentiate and prolong neuromuscular blockade by nondepolarizing agents. This is relevant mainly during anesthesia and recovery.
What this interaction means in plain words
Amlodipine-benazepril and Cisatracurium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amlodipine-benazepril belongs to Cardiovascular; Cisatracurium belongs to Musculoskeletal.
Why it happens
Calcium channel blockade reduces presynaptic acetylcholine release, adding to nondepolarizing blockade.
What to do
Use neuromuscular monitoring and titrate cisatracurium to effect, allowing for slower recovery.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Amlodipine-benazepril
- Aliskiren + Amlodipine-benazepril Contraindicated
- Amlodipine-benazepril + Sacubitril / valsartan Contraindicated
- Aldesleukin + Amlodipine-benazepril Major
- Amifostine + Amlodipine-benazepril Major
- Amiloride + Amlodipine-benazepril Major
- Amlodipine-benazepril + Azilsartan Major
Other interactions of Cisatracurium
Frequently asked questions
Can I take Amlodipine-benazepril with Cisatracurium?
MediHelp rates the interaction as moderate. Amlodipine-benazepril and Cisatracurium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Calcium channel blockers may potentiate and prolong neuromuscular blockade by nondepolarizing agents. This is relevant mainly during anesthesia and recovery.
How serious is the interaction between Amlodipine-benazepril and Cisatracurium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use neuromuscular monitoring and titrate cisatracurium to effect, allowing for slower recovery.
What other medicines interact with Amlodipine-benazepril?
MediHelp also lists interactions of Amlodipine-benazepril with, for example, Aliskiren, Sacubitril / valsartan, Aldesleukin. The full list is on the Amlodipine-benazepril page.
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