Drug interactions
Amlodipine-benazepril + Nebivolol
Severity: Moderate
Amlodipine-benazepril and Nebivolol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Combining a beta-blocker with a calcium channel blocker and an ACE inhibitor produces additive blood pressure lowering. This is often used intentionally, but it can cause symptomatic hypotension, bradycardia or dizziness, especially at initiation.
What this interaction means in plain words
Amlodipine-benazepril and Nebivolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amlodipine-benazepril belongs to Cardiovascular; Nebivolol belongs to Cardiovascular.
Why it happens
Additive pharmacodynamic antihypertensive effects through different pathways.
What to do
Monitor blood pressure and heart rate when starting or adjusting doses, and titrate gradually.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Amlodipine-benazepril
- Aliskiren + Amlodipine-benazepril Contraindicated
- Amlodipine-benazepril + Sacubitril / valsartan Contraindicated
- Aldesleukin + Amlodipine-benazepril Major
- Amifostine + Amlodipine-benazepril Major
- Amiloride + Amlodipine-benazepril Major
- Amlodipine-benazepril + Azilsartan Major
Other interactions of Nebivolol
- Acebutolol + Nebivolol Major
- Aldesleukin + Nebivolol Major
- Amiodarone + Nebivolol Major
- Atenolol-chlorthalidone + Nebivolol Major
- Atenolol + Nebivolol Major
- Betaxolol + Nebivolol Major
Frequently asked questions
Can I take Amlodipine-benazepril with Nebivolol?
MediHelp rates the interaction as moderate. Amlodipine-benazepril and Nebivolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Combining a beta-blocker with a calcium channel blocker and an ACE inhibitor produces additive blood pressure lowering. This is often used intentionally, but it can cause symptomatic hypotension, bradycardia or dizziness, especially at initiation.
How serious is the interaction between Amlodipine-benazepril and Nebivolol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate when starting or adjusting doses, and titrate gradually.
What other medicines interact with Amlodipine-benazepril?
MediHelp also lists interactions of Amlodipine-benazepril with, for example, Aliskiren, Sacubitril / valsartan, Aldesleukin. The full list is on the Amlodipine-benazepril page.
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