Drug interactions
Amlodipine-benazepril + Pancuronium
Severity: Minor
Amlodipine-benazepril and Pancuronium: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Calcium channel blockers may enhance and prolong neuromuscular blockade from nondepolarizing agents such as pancuronium. The clinical effect is usually modest but can lengthen recovery.
What this interaction means in plain words
Amlodipine-benazepril and Pancuronium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amlodipine-benazepril belongs to Cardiovascular; Pancuronium belongs to Musculoskeletal.
Why it happens
Calcium channel blockade reduces acetylcholine release at the neuromuscular junction, adding to nondepolarizing blockade.
What to do
Monitor neuromuscular function with a nerve stimulator and titrate pancuronium to effect. Be prepared for slower recovery.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine-benazepril
- Aliskiren + Amlodipine-benazepril Contraindicated
- Amlodipine-benazepril + Sacubitril / valsartan Contraindicated
- Aldesleukin + Amlodipine-benazepril Major
- Amifostine + Amlodipine-benazepril Major
- Amiloride + Amlodipine-benazepril Major
- Amlodipine-benazepril + Azilsartan Major
Other interactions of Pancuronium
Frequently asked questions
Can I take Amlodipine-benazepril with Pancuronium?
MediHelp rates the interaction as minor. Amlodipine-benazepril and Pancuronium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Calcium channel blockers may enhance and prolong neuromuscular blockade from nondepolarizing agents such as pancuronium. The clinical effect is usually modest but can lengthen recovery.
How serious is the interaction between Amlodipine-benazepril and Pancuronium?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor neuromuscular function with a nerve stimulator and titrate pancuronium to effect. Be prepared for slower recovery.
What other medicines interact with Amlodipine-benazepril?
MediHelp also lists interactions of Amlodipine-benazepril with, for example, Aliskiren, Sacubitril / valsartan, Aldesleukin. The full list is on the Amlodipine-benazepril page.
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