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Drug interactions

Amlodipine-benazepril + Potassium iodide

Severity: Moderate

Amlodipine-benazepril and Potassium iodide: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Potassium iodide contains potassium, and ACE inhibitors reduce potassium excretion, so serum potassium can rise. Risk is higher with prolonged use, renal impairment or other potassium-raising drugs.

What this interaction means in plain words

Amlodipine-benazepril and Potassium iodide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Amlodipine-benazepril belongs to Cardiovascular; Potassium iodide belongs to Endocrine.

Evidence level: Low

Why it happens

ACE inhibition decreases aldosterone-mediated potassium excretion, adding to the potassium load.

What to do

Monitor serum potassium and renal function when potassium iodide is used for more than short courses. Intervene if potassium becomes elevated.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Amlodipine-benazepril with Potassium iodide?

MediHelp rates the interaction as moderate. Amlodipine-benazepril and Potassium iodide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Potassium iodide contains potassium, and ACE inhibitors reduce potassium excretion, so serum potassium can rise. Risk is higher with prolonged use, renal impairment or other potassium-raising drugs.

How serious is the interaction between Amlodipine-benazepril and Potassium iodide?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium and renal function when potassium iodide is used for more than short courses. Intervene if potassium becomes elevated.

What other medicines interact with Amlodipine-benazepril?

MediHelp also lists interactions of Amlodipine-benazepril with, for example, Aliskiren, Sacubitril / valsartan, Aldesleukin. The full list is on the Amlodipine-benazepril page.

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