Drug interactions
Amlodipine-benazepril + Tamsulosin
Severity: Moderate
Amlodipine-benazepril and Tamsulosin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tamsulosin is an alpha-1 blocker that can cause orthostatic hypotension. Combined with an ACE inhibitor and calcium channel blocker, dizziness and fainting may be more likely.
What this interaction means in plain words
Amlodipine-benazepril and Tamsulosin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amlodipine-benazepril belongs to Cardiovascular; Tamsulosin belongs to Genitourinary.
Why it happens
Additive vasodilation and blood pressure lowering from alpha-1 blockade, ACE inhibition and calcium channel blockade.
What to do
Monitor blood pressure and orthostatic symptoms when tamsulosin is started, preferably at bedtime. Adjust antihypertensive doses if symptomatic hypotension occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Amlodipine-benazepril and Tamsulosin, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Amlodipine-benazepril
- Aliskiren + Amlodipine-benazepril Contraindicated
- Amlodipine-benazepril + Sacubitril / valsartan Contraindicated
- Aldesleukin + Amlodipine-benazepril Major
- Amifostine + Amlodipine-benazepril Major
- Amiloride + Amlodipine-benazepril Major
- Amlodipine-benazepril + Azilsartan Major
Other interactions of Tamsulosin
- Alfuzosin + Tamsulosin Major
- Avanafil + Tamsulosin Major
- Ceritinib + Tamsulosin Major
- Clarithromycin + Tamsulosin Major
- Cobicistat + Tamsulosin Major
- Doxazosin + Tamsulosin Major
Frequently asked questions
Can I take Amlodipine-benazepril with Tamsulosin?
MediHelp rates the interaction as moderate. Amlodipine-benazepril and Tamsulosin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Tamsulosin is an alpha-1 blocker that can cause orthostatic hypotension. Combined with an ACE inhibitor and calcium channel blocker, dizziness and fainting may be more likely.
How serious is the interaction between Amlodipine-benazepril and Tamsulosin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and orthostatic symptoms when tamsulosin is started, preferably at bedtime. Adjust antihypertensive doses if symptomatic hypotension occurs.
What other medicines interact with Amlodipine-benazepril?
MediHelp also lists interactions of Amlodipine-benazepril with, for example, Aliskiren, Sacubitril / valsartan, Aldesleukin. The full list is on the Amlodipine-benazepril page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
