Drug interactions
Amlodipine-benazepril + Tinidazole
Severity: Minor
Amlodipine-benazepril and Tinidazole: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Amlodipine is a weak CYP3A4 inhibitor, and tinidazole is partly metabolized by CYP3A4, so a rise in tinidazole exposure is theoretically possible. Any change is expected to be small and unlikely to be clinically important.
What this interaction means in plain words
Amlodipine-benazepril and Tinidazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amlodipine-benazepril belongs to Cardiovascular; Tinidazole belongs to Anti Parasitic.
Why it happens
Weak inhibition of CYP3A4 by amlodipine may slightly reduce tinidazole metabolism.
What to do
No routine adjustment is needed. Be aware of increased tinidazole adverse effects such as nausea or metallic taste.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine-benazepril
- Aliskiren + Amlodipine-benazepril Contraindicated
- Amlodipine-benazepril + Sacubitril / valsartan Contraindicated
- Aldesleukin + Amlodipine-benazepril Major
- Amifostine + Amlodipine-benazepril Major
- Amiloride + Amlodipine-benazepril Major
- Amlodipine-benazepril + Azilsartan Major
Other interactions of Tinidazole
- Disulfiram + Tinidazole Contraindicated
- Ethanol + Tinidazole Major
- Fexinidazole + Tinidazole Major
- Lopinavir + Tinidazole Major
- Nilotinib + Tinidazole Major
- Ritonavir + Tinidazole Major
Frequently asked questions
Can I take Amlodipine-benazepril with Tinidazole?
MediHelp rates the interaction as minor. Amlodipine-benazepril and Tinidazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Amlodipine is a weak CYP3A4 inhibitor, and tinidazole is partly metabolized by CYP3A4, so a rise in tinidazole exposure is theoretically possible. Any change is expected to be small and unlikely to be clinically important.
How serious is the interaction between Amlodipine-benazepril and Tinidazole?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed. Be aware of increased tinidazole adverse effects such as nausea or metallic taste.
What other medicines interact with Amlodipine-benazepril?
MediHelp also lists interactions of Amlodipine-benazepril with, for example, Aliskiren, Sacubitril / valsartan, Aldesleukin. The full list is on the Amlodipine-benazepril page.
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