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Drug interactions

Amlodipine-benazepril + Vecuronium

Severity: Minor

Amlodipine-benazepril and Vecuronium: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Calcium channel blockers may potentiate neuromuscular blockade from vecuronium. Recovery may be prolonged, although the effect is usually small.

What this interaction means in plain words

Amlodipine-benazepril and Vecuronium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Amlodipine-benazepril belongs to Cardiovascular; Vecuronium belongs to Musculoskeletal.

Evidence level: Low

Why it happens

Calcium channel blockade reduces presynaptic acetylcholine release, adding to nondepolarizing blockade.

What to do

Use neuromuscular monitoring and titrate vecuronium to effect. Expect possibly slower recovery.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Amlodipine-benazepril with Vecuronium?

MediHelp rates the interaction as minor. Amlodipine-benazepril and Vecuronium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Calcium channel blockers may potentiate neuromuscular blockade from vecuronium. Recovery may be prolonged, although the effect is usually small.

How serious is the interaction between Amlodipine-benazepril and Vecuronium?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use neuromuscular monitoring and titrate vecuronium to effect. Expect possibly slower recovery.

What other medicines interact with Amlodipine-benazepril?

MediHelp also lists interactions of Amlodipine-benazepril with, for example, Aliskiren, Sacubitril / valsartan, Aldesleukin. The full list is on the Amlodipine-benazepril page.

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