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Drug interactions

Amlodipine-olmesartan + Calcium carbonate

Severity: Minor

Amlodipine-olmesartan and Calcium carbonate: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Oral calcium supplements at usual doses have little effect on amlodipine, though high intravenous calcium can reduce calcium channel blocker effect. Clinically significant loss of blood pressure control with oral calcium carbonate is unlikely.

What this interaction means in plain words

Amlodipine-olmesartan and Calcium carbonate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Amlodipine-olmesartan belongs to Cardiovascular; Calcium carbonate belongs to Gastrointestinal Tract.

Evidence level: Low

Why it happens

Elevated extracellular calcium may theoretically oppose calcium channel blockade.

What to do

No action is generally required; monitor blood pressure if large calcium doses are used.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Amlodipine-olmesartan with Calcium carbonate?

MediHelp rates the interaction as minor. Amlodipine-olmesartan and Calcium carbonate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oral calcium supplements at usual doses have little effect on amlodipine, though high intravenous calcium can reduce calcium channel blocker effect. Clinically significant loss of blood pressure control with oral calcium carbonate is unlikely.

How serious is the interaction between Amlodipine-olmesartan and Calcium carbonate?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action is generally required; monitor blood pressure if large calcium doses are used.

What other medicines interact with Amlodipine-olmesartan?

MediHelp also lists interactions of Amlodipine-olmesartan with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Amlodipine-olmesartan page.

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