Drug interactions
Atenolol + Calcium carbonate
Severity: Moderate
Atenolol and Calcium carbonate: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Calcium salts can reduce atenolol absorption, lowering its blood levels and possibly weakening heart rate and blood pressure control. The effect is modest but reported.
What this interaction means in plain words
Atenolol and Calcium carbonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atenolol belongs to Cardiovascular; Calcium carbonate belongs to Gastrointestinal Tract.
Why it happens
Calcium reduces gastrointestinal absorption of atenolol, probably through binding or complexation.
What to do
Separate atenolol from calcium carbonate by at least 2 hours, and monitor heart rate and blood pressure.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Calcium carbonate
- Acalabrutinib + Calcium carbonate Moderate
- Alendronate + Calcium carbonate Moderate
- Amlodipine-hydrochlorothiazide-valsartan + Calcium carbonate Moderate
- Amlodipine-olmesartan-hydrochlorothiazide + Calcium carbonate Moderate
- Atazanavir + Calcium carbonate Moderate
- Azilsartan-chlorthalidone + Calcium carbonate Moderate
Other interactions of Atenolol
- Amifostine + Atenolol Major
- Amiodarone + Atenolol Major
- Atenolol + Atenolol-chlorthalidone Major
- Atenolol + Betaxolol Major
- Atenolol + Bisoprolol Major
- Atenolol + Carvedilol Major
Frequently asked questions
Can I take Atenolol with Calcium carbonate?
MediHelp rates the interaction as moderate. Atenolol and Calcium carbonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Calcium salts can reduce atenolol absorption, lowering its blood levels and possibly weakening heart rate and blood pressure control. The effect is modest but reported.
How serious is the interaction between Atenolol and Calcium carbonate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate atenolol from calcium carbonate by at least 2 hours, and monitor heart rate and blood pressure.
What other medicines interact with Calcium carbonate?
MediHelp also lists interactions of Calcium carbonate with, for example, Acalabrutinib, Alendronate, Amlodipine-hydrochlorothiazide-valsartan. The full list is on the Calcium carbonate page.
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