Drug interactions
Amlodipine-olmesartan + Calcium gluconate
Severity: Minor
Amlodipine-olmesartan and Calcium gluconate: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Calcium gluconate given intravenously can counteract calcium channel blocker effects and is used to treat their toxicity. In patients on amlodipine it may reduce blood pressure control transiently. Oral doses have little practical effect.
What this interaction means in plain words
Amlodipine-olmesartan and Calcium gluconate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amlodipine-olmesartan belongs to Cardiovascular; Calcium gluconate belongs to Gastrointestinal Tract.
Why it happens
Increased extracellular calcium overcomes L-type calcium channel blockade by amlodipine.
What to do
Monitor blood pressure when IV calcium gluconate is given; no change is needed for oral supplementation with normal calcium levels.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine-olmesartan
- Aliskiren + Amlodipine-olmesartan Contraindicated
- Amlodipine-olmesartan + Sparsentan Contraindicated
- Amifostine + Amlodipine-olmesartan Major
- Amiloride + Amlodipine-olmesartan Major
- Amlodipine-olmesartan + Benazepril Major
- Amlodipine-olmesartan + Captopril Major
Other interactions of Calcium gluconate
- Calcium gluconate + Ceftriaxone Contraindicated
- Calcium gluconate + Digoxin Major
- Alendronate + Calcium gluconate Moderate
- Amlodipine-atorvastatin + Calcium gluconate Moderate
- Amlodipine-hydrochlorothiazide-valsartan + Calcium gluconate Moderate
- Amlodipine-olmesartan-hydrochlorothiazide + Calcium gluconate Moderate
Frequently asked questions
Can I take Amlodipine-olmesartan with Calcium gluconate?
MediHelp rates the interaction as minor. Amlodipine-olmesartan and Calcium gluconate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Calcium gluconate given intravenously can counteract calcium channel blocker effects and is used to treat their toxicity. In patients on amlodipine it may reduce blood pressure control transiently. Oral doses have little practical effect.
How serious is the interaction between Amlodipine-olmesartan and Calcium gluconate?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure when IV calcium gluconate is given; no change is needed for oral supplementation with normal calcium levels.
What other medicines interact with Amlodipine-olmesartan?
MediHelp also lists interactions of Amlodipine-olmesartan with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Amlodipine-olmesartan page.
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