Drug interactions
Amlodipine-olmesartan + Dasatinib
Severity: Minor
Amlodipine-olmesartan and Dasatinib: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dasatinib is a time-dependent CYP3A4 inhibitor and may modestly increase amlodipine exposure. This could cause more hypotension or edema, although dasatinib itself also causes fluid retention.
What this interaction means in plain words
Amlodipine-olmesartan and Dasatinib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amlodipine-olmesartan belongs to Cardiovascular; Dasatinib belongs to Oncology.
Why it happens
Dasatinib inhibits CYP3A4, reducing amlodipine metabolism.
What to do
Monitor blood pressure and edema; reduce the amlodipine dose if hypotension or marked edema develops.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine-olmesartan
- Aliskiren + Amlodipine-olmesartan Contraindicated
- Amlodipine-olmesartan + Sparsentan Contraindicated
- Amifostine + Amlodipine-olmesartan Major
- Amiloride + Amlodipine-olmesartan Major
- Amlodipine-olmesartan + Benazepril Major
- Amlodipine-olmesartan + Captopril Major
Other interactions of Dasatinib
- Dasatinib + Saquinavir Contraindicated
- Dasatinib + Thioridazine Contraindicated
- Adagrasib + Dasatinib Major
- Amiodarone + Dasatinib Major
- Amisulpride + Dasatinib Major
- Amitriptyline + Dasatinib Major
Frequently asked questions
Can I take Amlodipine-olmesartan with Dasatinib?
MediHelp rates the interaction as minor. Amlodipine-olmesartan and Dasatinib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Dasatinib is a time-dependent CYP3A4 inhibitor and may modestly increase amlodipine exposure. This could cause more hypotension or edema, although dasatinib itself also causes fluid retention.
How serious is the interaction between Amlodipine-olmesartan and Dasatinib?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and edema; reduce the amlodipine dose if hypotension or marked edema develops.
What other medicines interact with Amlodipine-olmesartan?
MediHelp also lists interactions of Amlodipine-olmesartan with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Amlodipine-olmesartan page.
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