Drug interactions
Amlodipine-olmesartan + Succinylcholine
Severity: Minor
Amlodipine-olmesartan and Succinylcholine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Calcium channel blockers may potentiate neuromuscular blockade, and the effect with amlodipine and a depolarizing agent is small and poorly documented. It may matter mainly during anesthesia.
What this interaction means in plain words
Amlodipine-olmesartan and Succinylcholine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amlodipine-olmesartan belongs to Cardiovascular; Succinylcholine belongs to Musculoskeletal.
Why it happens
Calcium channel blockade may reduce presynaptic acetylcholine release, augmenting neuromuscular blockade.
What to do
Use neuromuscular monitoring during anesthesia and titrate succinylcholine to effect.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine-olmesartan
- Aliskiren + Amlodipine-olmesartan Contraindicated
- Amlodipine-olmesartan + Sparsentan Contraindicated
- Amifostine + Amlodipine-olmesartan Major
- Amiloride + Amlodipine-olmesartan Major
- Amlodipine-olmesartan + Benazepril Major
- Amlodipine-olmesartan + Captopril Major
Other interactions of Succinylcholine
Frequently asked questions
Can I take Amlodipine-olmesartan with Succinylcholine?
MediHelp rates the interaction as minor. Amlodipine-olmesartan and Succinylcholine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Calcium channel blockers may potentiate neuromuscular blockade, and the effect with amlodipine and a depolarizing agent is small and poorly documented. It may matter mainly during anesthesia.
How serious is the interaction between Amlodipine-olmesartan and Succinylcholine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use neuromuscular monitoring during anesthesia and titrate succinylcholine to effect.
What other medicines interact with Amlodipine-olmesartan?
MediHelp also lists interactions of Amlodipine-olmesartan with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Amlodipine-olmesartan page.
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